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Quintessence International



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Quintessence Int 26 (1995), No. 11     1. Nov. 1995
Quintessence Int 26 (1995), No. 11  (01.11.1995)

Page 795-803

Papillon-Lefevre syndrome--Successful treatment with a combination of retinoid and concurrent systematic periodontal therapy: Case reports
Kressin / Herforth / Preis / Wahn / Lenard
Papillon-Lefevre syndrome is a rare autosomal-recessive congenital differentiation disorder; the external signs are hyperkeratosis of the palms and soles. Intraorally, the most salient manifestations are dystrophic periodontal that affect both the primary and permanent dentitions and frequently lead to premature tooth loss. Two children were treated with acitretin 0.5 mg/kg of body weight per day from November 1992 to November 1993, and another child since October 1993. Concurrently, the children received professional oral hygiene care (scaling, root planning, and curettage). The combination of retinoid therapy and periodontal treatment improved the dermatologic and periodontal conditions.