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Quintessence International



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Quintessence Int 28 (1997), No. 3     1. Mar. 1997
Quintessence Int 28 (1997), No. 3  (01.03.1997)

Page 169-171

Preoperative prophylaxis for C1 esterase-inhibitor deficiency in patients undergoing oral surgery: A report of three cases
Peled / Ardekian / Schnarch / Laufer
C1-inhibitor deficiency, or hereditary angioedema, is a genetic disorder characterized by recurrent circumscribed, nonpruritic, nonpitting subepithelial edema. Minor trauma to the tissue, such as tooth extraction, can trigger life-threatening laryngeal edema. The use of fresh forzen plasma and/or danazol before treatment prevents angioedema attacks. A critical review of the treatment regimen and prophylaxis for C1-inhibitor deficiency is presented, and thre e new cases are described.