Quintessence Int 28 (1997), No. 3 (01.03.1997)
Page 169-171
Preoperative prophylaxis for C1 esterase-inhibitor deficiency in patients undergoing oral surgery: A report of three cases
Peled / Ardekian / Schnarch / Laufer
C1-inhibitor deficiency, or hereditary angioedema, is a genetic disorder characterized by recurrent circumscribed, nonpruritic, nonpitting subepithelial edema. Minor trauma to the tissue, such as tooth extraction, can trigger life-threatening laryngeal edema. The use of fresh forzen plasma and/or danazol before treatment prevents angioedema attacks. A critical review of the treatment regimen and prophylaxis for C1-inhibitor deficiency is presented, and thre e new cases are described.