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Quintessence International



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Quintessence Int 42 (2011), No. 4     2. Mar. 2011
Quintessence Int 42 (2011), No. 4  (02.03.2011)

Page 301-306, PubMed:21516275

Radiographic evaluation of periapical lesions with and without biopsy-proven actinomyces: A pilot study
Kuklani, Riya M. / Bhattacharyya, Indraneel / Nair, Madhu K.
Objective: To explore the feasibility of identifying potential radiometric differences in periapical radiolucencies with and without actinomycotic colonization as seen on periapical radiographs using histopathology for ground truth.
Method and Materials: Periapical radiographs demonstrating apical lesions with and without biopsy-proven actinomycosis were included in the study. Lesion sizes were estimated on standardized images using anatomical reference points. The reading session was repeated after 2 weeks, and mean lesion sizes were calculated. All measurements were made by a single, calibrated observer.
Results: The mean dimension of lesions with actinomyces was 13.51 × 16.43 mm, while lesions without actinomyces had a mean size of 10.24 × 11.27 mm.
Conclusion: Apical lesions with biopsy-proven actinomyces may be larger in dimension than those without bacterial colonization. Further controlled studies are required to confirm this finding.

Keywords: actinomyces, histology, intraoral, periapical, radiographic