Quintessence Int 40 (2009), No. 10 1. Oct. 2009
Quintessence Int 40 (2009), No. 10 (01.10.2009)
Page 805-808, PubMed:19898711
Primary extranodal non-Hodgkin lymphoma of the gingiva initially misdiagnosed as dental abscess
Martinelli-Kläy, Carla Patrícia / Martinelli, Celso Ricardo / Martinelli, Celso / Dias, José Beneditio / Cheade, Teresa Cristina / Lombardi, Tommaso
Oral non-Hodgkin lymphomas are uncommon, and those arising on the gingiva are rare. A case of non-Hodgkin lymphoma of the gingiva that was erroneously diagnosed and treated as a dental abscess is presented. Clinical examination showed a firm and ulcerated mass extending from the mandibular right first premolar region to the retromolar trigone. Resorption of the alveolar ridge was radiographically observed. Histologic analysis revealed a large B-cell non-Hodgkin lymphoma. No other evidence of the disease was found except in the mandible. The patient was treated with chemotherapy that resulted in complete regression. As primary non-Hodgkin lymphoma of the gingiva can be misdiagnosed as a trivial inflammatory lesion, a histologic examination should be mandatory in those cases in which symptoms do not subside after specific treatment.
Keywords: differential diagnosis, gingiva, immunohistochemistry, non-Hodgkin lymphomas, oral cavity