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Quintessence International



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Quintessence Int 38 (2007), No. 6     30. May 2007
Quintessence Int 38 (2007), No. 6  (30.05.2007)

Online Article, Page 528, PubMed:17625621

Online Article: In vitro antimicrobial activity of peroxide-based bleaching agents
Napimoga, Marcelo Henrique / de Oliveira, Rogerio / Reis, Andre Figueiredo / Gonçalves, Reginaldo Bruno / Giannini, Marcelo
Antibacterial activity of 4 commercial bleaching agents (Day White, Colgate Platinum, Whiteness 10% and 16%) on 6 oral pathogens (Streptococcus mutans, Streptococcus sobrinus, Streptococcus sanguinis, Candida albicans, Lactobacillus casei, and Lactobacillus acidophilus) and Staphylococcus aureus were evaluated. A chlorhexidine solution was used as a positive control, while distilled water was the negative control. Bleaching agents and control materials were inserted in sterilized stainless-steel cylinders that were positioned under inoculated agar plate (n = 4). After incubation according to the appropriate period of time for each microorganism, the inhibition zones were measured. Data were analyzed by 2-way analysis of variance and Tukey test (a = 0.05). All bleaching agents and the chlorhexidine solution produced antibacterial inhibition zones. Antimicrobial activity was dependent on peroxide-based bleaching agents. For most microorganisms evaluated, bleaching agents produced inhibition zones similar to or larger than that observed for chlorhexidine. C albicans, L casei, and L acidophilus were the most resistant microorganisms.

Keywords: antimicrobial activity. bleaching agent, carbamide peroxide, oral microorganism