We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
Quintessence International



Forgotten password?


Quintessence Int 40 (2009), No. 4     26. Feb. 2009
Quintessence Int 40 (2009), No. 4  (26.02.2009)

Page 279-285, PubMed:19417872

Effect of xylitol and sorbitol on plaque acidogenesis
Splieth, Christian H. / Alkilzy, Mohammad / Schmitt, Jan / Berndt, Christine / Welk, Alexander
Objective: To evaluate the in vivo potential of xylitol to reduce plaque acidogenicity in comparison to sorbitol.
Method and Materials: After completing a questionnaire on general health, smoking, diet, and oral hygiene habits, 61 dentate adults refrained from oral hygiene for 3 days before the clinical baseline examination, which included decayed, missing, and filled teeth (DMFT) index, mutans streptococci and lactobacilli counts, and plaque acidogenicity (cH) index after a sucrose rinse. Then the participants were randomly allocated to consume either sorbitol or xylitol lozenges (5 pieces/day, 2 g each) for 4 weeks and were asked to refrain from oral hygiene for the 3 days prior to the final examination (cH, area < pH 7, bacterial counts).
Results: The variation of acidogenicity in different individuals was considerable at baseline (range: 0.2 to 446.6 min*µmol/L) with a mean value of 37.9 ± 58.9 min*µmol/L for the sorbitol group and 60.6 ± 87.6 min*µmol/L for the xylitol group. At the end of the study, the reduction in the xylitol group (42.9 ± 80.6 min*µmol/L) was statistically significantly higher than in the sorbitol group (6.0 ± 69.4 min*µmol/L, P = .034), which was also confirmed in an additional analysis excluding 2 participants with extreme values (reduction for xylitol: 29.5 ± 36.9 min*µmol/L; sorbitol: 1.7 ± 57.0 min*µmol/L; P = .019). Statistically significant differences were also found for the area below pH 7 (reduction for xylitol: 10.8 min pH; sorbitol, 0.2 min pH; P = .0025).
Conclusion: The regular consumption of xylitol lozenges modifies dental plaque, resulting in a marked reduction in the plaque acidogenicity, which could not be detected using sorbitol lozenges. Therefore, xylitol could have an additional benefit in caries prevention.

Keywords: acidogenicity, caries, cH index, plaque, prevention, sorbitol, xylitol