We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
Quintessence International
Login:
username:

password:

Plattform:

Forgotten password?

Registration

Quintessence Int 38 (2007), No. 7     14. June 2007
Quintessence Int 38 (2007), No. 7  (14.06.2007)

Page 601-606, PubMed:17694218


Efficacy of 1% ropivacaine gel for topical anesthesia of human oral mucosa
Franz-Montan, Michelle / Silva, André Luis Rotolo / Cogo, Karina / Bergamaschi, Cristiane / Volpato, Maria Cristina / Ranali, José / de Paula, Eneida / Groppo, Francisco Carlos
Objective: To evaluate the efficacy of 1% ropivacaine for topical anesthesia in dentistry.
Method and Materials: Thirty healthy volunteers randomly (blind crossover) received the following treatments: 20 mg of 1% ropivacaine gel (ropivacaine-20), 60 mg of 1% ropivacaine gel (ropivacaine-60), 20 mg of the eutectic mixture of local anesthetics 2.5% lidocaine and 2.5% prilocaine (EMLA cream, AstraZeneca; EMLA-20), 60 mg of EMLA (EMLA-60), 20 mg of 20% benzocaine gel (Benzotop, DFL; benzocaine-20), and 60 mg of 20% benzocaine gel (benzocaine-60), applied on the maxillary buccal fold of the right canine at different sessions. Pain was assessed by visual analog scale (VAS) and 11-point box scale (BS-11) after the insertion of 30-gauge needles. Soft tissue anesthesia was measured by pinprick test. Data were analyzed by Friedman and Pearson correlation tests.
Results: All the topical anesthetics evaluated showed similar performance in relation to the pain perceived after needle insertion (P > .05), and there were no significant differences among groups considering VAS or BS-11 (P = .177 and P = .179, respectively). The duration of soft tissue anesthesia was not statistically significantly different for ropivacaine-20, EMLA-20, benzocaine-20, ropivacaine-60, EMLA-60, and benzocaine-60, but EMLA-60 showed significantly longer duration than the other agents (P < .05).
Conclusion: All topical anesthetics were similar in reducing pain to needle insertion. EMLA-60 promoted longer duration of soft tissue anesthesia.

Keywords: benzocaine, eutectic mixture of lidocaine and prilocaine, local anesthesia, oral mucosa, ropivacaine, topical anesthesia, topical anesthetic