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Quintessence International
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Quintessence Int 37 (2006), No. 5     5. Apr. 2006
Quintessence Int 37 (2006), No. 5  (05.04.2006)

Page 391-394, PubMed:16683687


In vitro antibacterial efficacy of a new chlorhexidine slow-release device
Lin, Shaul / Levin, Liran / Weiss, Ervin Izhak / Peled, Micha / Fuss, Zvi
Objective: The aim of this study was to evaluate and compare the antibacterial effect of chlorhexidine and calcium hydroxide slow-release devices on oral bacteria.
Method and Materials: The agar diffusion test was used to evaluate the antibacterial effect of the slow-release devices Activ Point (chlorhexidine; Roeko) and Calcium Hydroxide Plus Point (Roeko) on 8 anaerobic and 2 facultative oral bacterial strains, as well as 2 bacterial cultures randomly sampled from necrotic root canals and incubated in anaerobic and aerobic broth for 48 hours. The efficiency of the medicaments against the various strains was evaluated using a nonparametric test (Friedman type) and a second nonparametric test (Wilcoxon's signed rank test).
Results: Activ Point produced significantly larger inhibition zones (P < .001) than the calcium hydroxide slow-release device around all tested bacterial strains.
Conclusion: The chlorhexidine slow-release device (Activ Point) exhibited significant antibacterial activity in the agar diffusion test and merits study as an intracanal medicament.

Keywords: agar diffusion test, calcium hydroxide, chlorhexidine, slow-release device