our online journals are moving. The new (and old) issues of all journals can be found at
In most cases you can log in there directly with your e-mail address and your current password. Otherwise we ask you to register again. Thank you very much.
Your Quintessence Publishing House
Quintessence Int 51 (2020), No. 10 16. Oct. 2020
Quintessence Int 51 (2020), No. 10 (16.10.2020)
Page 788-797, doi:10.3290/j.qi.a45173, PubMed:32901243
Bleaching sensitivity with a desensitizing in-office bleaching gel: a randomized double-blind clinical trial
Maran, Bianca Medeiros / Vochikovski, Laína / Hortkoff, Diego Rafael de Andrade / Stanislawczuk, Rodrigo / Loguercio, Alessandro D. / Reis, Alessandra
Objectives: This split-mouth study assessed the bleaching sensitivity (risk and intensity) and color change after in-office bleaching using a desensitizing-containing (5% potassium nitrate) and a desensitizing-free 35% hydrogen peroxide gel. The null hypothesis was that there would be no differences between study groups regarding bleaching sensitivity.
Method and materials: Sixty patients participated in this split-mouth study. The subjects received desensitizing-containing hydrogen peroxide in half of the maxillary arch, and the other half received a desensitizing-free hydrogen peroxide, defined by random sequence, in two dental bleaching sessions. The bleaching sensitivity was evaluated during bleaching and from 1 h to 48 h after each bleaching session using a visual analog scale and numeric rating scale; the McNemar test, the Wilcoxon signed-rank test, and the Student-Newman-Keuls test were used for statistical analysis. The color was measured at baseline and 30 days post-bleaching, evaluated with paired t tests (P = .05).
Results: Statistically similar risks of bleaching sensitivity were observed (P = 1.000), but the intensity of bleaching sensitivity was lower (P < .011) on average by 1.32 visual analog scale units in the group bleached with the desensitizer-containing gel during up to 24 h assessment times. No statistical difference in color change was observed between groups (P > .321).
Conclusion: The incorporation of 5% potassium nitrate into in-office bleaching gels does not reduce the risk of bleaching sensitivity, but it reduces its intensity slightly without jeopardizing color change.
Keywords: dentin sensitivity, hydrogen peroxide, randomized controlled trial, tooth bleaching agents