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Quintessence Int 46 (2015), No. 9     19. Aug. 2015
Quintessence Int 46 (2015), No. 9  (19.08.2015)

Page 773-780, doi:10.3290/j.qi.a34457, PubMed:26159211


Radiographic outcomes following treatment of intrabony defects by freeze-dried bone allograft combined with enamel matrix derivative: A retrospective study
Tartakovsky, Yelena / Goldstein, Ayana / Goldstein, Moshe
Objective: The aim of this study was to evaluate the radiographic outcomes following regenerative surgery using enamel matrix derivative (EMD) + freeze-dried bone allograft (FDBA).
Method and Materials: In total, 74 two- or three-wall intrabony defects were treated by a combination of EMD+FDBA followed by supportive periodontal therapy (SPT) for a minimum of 2 years. Radiographs were taken at baseline and after the follow-up period. The measurements taken were: baseline defect angle, CEJ to the coronal part of the alveolar bone crest (CEJ-BC), CEJ to the apical part of the intrabony defect (CEJ- BD), the intrabony component of the defect (DL), and the defect angle between the lines CEJ-BC and CEJ-BD.
Results: Baseline defect angles were divided into three groups: first group defect angle ≤ 22 degrees; second group 22 degrees to 36 degrees; and third group ≥ 36 degrees. A significant difference in DL following treatment was found in all groups (6.930 mm, 4.202 mm, and 2.073 mm respectively; P < .01). The largest difference in DL was measured for the first group. A positive linear correlation was found between baseline values of the defect angle, CEJ-BD, CEJ-BC, and the later change in DL (P < .01).
Conclusion: The use of EMD+FDBA results in radiographic bone gain. Narrow defect angle and the depth of the intrabony component have significant positive correlation to radiographic bone gain.

Keywords: defect angle, depth of the intrabony component, enamel matrix derivative, freeze-dried bone allograft, radiographic bone gain, regeneration