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Quintessence International



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Quintessence Int 46 (2015), No. 5     27. Mar. 2015
Quintessence Int 46 (2015), No. 5  (27.03.2015)

Page 417-422, doi:10.3290/j.qi.a33180, PubMed:25485317

Hereditary angioedema and anxiety in oral surgery: A case series report
Zanette, Gastone / Stellini, Edoardo / Sivolella, Stefano / Bacci, Christian / Facco, Enrico
Hereditary angioedema (HAE) is a rare disease, little known to medical and dental practitioners, but with an increasing hospitalization rate over the years. HAE is due to a C1 esterase inhibitor deficiency/dysfunction that leads to an increased vascular permeability. The airways are the most affected, and life-threatening laryngeal swelling may occur. Episodes of HAE have no clear cause, but they can be triggered by anxiety, invasive procedures, and trauma. HAE is an important issue in oral and maxillofacial surgery, otorhinolaryngology, endoscopy, emergency medicine, and anesthesiology because even simple procedures may cause laryngeal edema. Recommendations on the management of HAE include long- and short-term prophylaxis, and treatment for acute attacks, but the importance of controlling anxiety is underestimated. Here, we report on the perioperative management of nine HAE patients scheduled for oral surgery, with a brief review of the literature on this topic.

Keywords: anxiety, conscious sedation, dentistry, hereditary angioedema, oral surgery